Technology

Expanding what’s possible in veterinary treatment.

Cardiac

FUNCTION

LIPUS applies controlled ultrasound energy to cardiac tissue, inducing biological effects that influence vascular and endothelial function, myocardial function, inflammation and tissue remodeling, cardiac electrophysiology, and autonomic regulation, thereby supporting cardiac function.

VASCULAR & ENDOTHELIAL RESPONSE

Supports endothelial function and vascular responses associated with improved microcirculation and myocardial perfusion.

MYOCARDIAL FUNCTION

Supports myocardial contraction and relaxation, while influencing cellular processes involved in cardiac energy metabolism.

REMODELING & INFLAMMATION

Modulates inflammatory and fibrotic processes associated with adverse cardiac remodeling and myocardial tissue integrity.

ELECTROPHYSIOLOGICAL & AUTONOMIC REGULATION

Influences cardiac electrical activity and autonomic regulation associated with rhythm stability and cardiovascular function.

adaptive

materials

ThermoAdapt uses thermoresponsive material properties to change from a flowable liquid at low temperature to a conformable gel near body temperature. This adaptive transition enables the material to cover wound surfaces and provide a physical environment that supports wound protection and healing.

THERMORESPONSIVE TRANSITION

Remains flowable at 36–46°F (2–8°C) and transitions into a non-flowing, conformable gel at 77–99°F (25–37°C).

ADAPTIVE WOUND COVERAGE

The flowable-to-gel transition allows the material to adapt to wound surfaces and maintain localized coverage after gel formation.

PHYSICAL PROTECTION

Forms a physical barrier over the wound surface, supporting protection of the wound during the healing process.

MOIST WOUND ENVIRONMENT

Helps maintain a moist local environment that supports wound healing and wound care.

SCIENTIFIC

LITERATURE

Selected scientific literature related to the technologies, biological effects, and clinical principles underlying our work, providing scientific context for our approach to veterinary medicine.

Low-Intensity Pulsed Ultrasound Induces Angiogenesis and Ameliorates Left Ventricular Dysfunction in a Porcine Model of Chronic Myocardial Ischemia

Porcine study investigating the effects of LIPUS on myocardial angiogenesis, regional myocardial blood flow, and left ventricular function in chronic myocardial ischemia.
PLOS ONE · 2014

Low-Intensity Pulsed Ultrasound Enhances Angiogenesis and Ameliorates Left Ventricular Dysfunction in a Mouse Model of Acute Myocardial Infarction

Mouse study investigating the effects of LIPUS on myocardial angiogenesis and left ventricular remodeling following acute myocardial infarction.
ARTERIOSCLER THROMB VASC BIOL · 2016

Low-Intensity Pulsed Ultrasound Ameliorates Cardiac Diastolic Dysfunction in Mice: A Possible Novel Therapy for Heart Failure With Preserved Left Ventricular Ejection FractionDescription

Mouse study investigating the effects of LIPUS on cardiac diastolic function in an experimental model of heart failure with preserved ejection fraction.
CARDIOVASC RES · 2021

Protective Effects of Low-Intensity Pulsed Ultrasound on Cardiac Electrophysiological Function in a Rat Model of Ischemic Cardiomyopathy

Rat study investigating the effects of LIPUS on cardiac electrophysiological function, ventricular remodeling, autonomic function, and arrhythmia risk in ischemic cardiomyopathy.
J AM HEART ASSOC · 2025

Low-Intensity Pulsed Ultrasound Attenuates Cardiac Inflammation of CVB3-Induced Viral Myocarditis via Regulation of Caveolin-1 and MAPK Pathways

Mouse study investigating the effects of LIPUS on cardiac inflammation, ventricular dysfunction, and inflammatory signaling in CVB3-induced viral myocarditis.
J CELL MOL MED · 2019